In collaboration with Scientific Association of Iranian Medicinal Plants
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Volume 1 (1999)
Evaluation effect of silymarin and vitamin C on myoglobinuric renal toxicity in rats

H. Najafzadeh Varzi; M. Sabzevarizadeh; R. Hajhosseini; Gh. Khajeh

Volume 28, Issue 3 , November 2012, , Pages 472-483

https://doi.org/10.22092/ijmapr.2012.2951

Abstract
  Rhabdomyolysis is an injury of skeletal muscle and it causes leakage of cellular contents including myoglobine. Myoglobinuria may produce acute renal failure due to the oxidative reactions. In the present study, the effect of silymarin and vitamin C (as natural antioxidant) was compared on myoglobinuric ...  Read More

Protective effect of silymarin and vitamin E on gentamicin-induced pathological changes in kidney of dog

H. Najafzadeh; S. Esmailzadeh; H. Morovvati; R. Avizeh; M. Ezati

Volume 26, Issue 1 , May 2010, , Pages 91-100

https://doi.org/10.22092/ijmapr.2010.6984

Abstract
  Drug-induced nephrotoxicity is an important factor for renal failure in dogs. Aminoglycosides including gentamicin could produce nephrotoxicity in dogs. The oxidative stress might be the case. Silymarin (extract seed of silybum marianum) is a potent antioxidant. In present study, the effect of silymarin ...  Read More